SLICC has been involved in many projects over the years. Catch up on them here.

WELCOME

OUR MISSION

The Systemic Lupus Erythematosus International Collaborating Clinics (SLICC) is an international group of rheumatologists and immunologists with special interests in lupus who have been working together on lupus research since 1991.

Towards a better world for people with lupus through prevention and improved outcomes

SLICC relies completely on the generosity and support of our donors and funders to continue our work.

SLICC group photo

SLICC developed the Damage Index

This is the only internationally accepted way of measuring the long-term effects of lupus and its treatment on the body. Without this index, it would be impossible to study those effects over time and compare them between different countries, geographies, and ethnic groups.

SLICC carried out the largest ever study of cancer in patients with lupus

This taught us that only some cancers are more likely to occur in patients with lupus and that the drugs commonly used to treat this disease do not significantly increase this risk of cancer.
SLICC group photo

HISTORY & OBJECTIVES

ABOUT SLICC

Since its inception over 25 years ago, SLICC has evolved into a dynamic and expanding research group helping to promote lupus research and collaboration between scientific investigators. Over its history, SLICC has contributed to the development of multiple standardized outcome measures to better characterize lupus activity and damage as well as its response to varying treatments.

CURRENT ACTIVITIES

SLICC'S RESEARCH

microscope

SLICC is dedicated to generating new knowledge in the field of lupus, and translating these basic and clinical research discoveries into better health care practices and policies to help provide a healthier future for people diagnosed with lupus.

In 1998, the SLICC group established a longitudinal cohort of newly diagnosed patients with lupus (SLICC Inception Cohort) to better understand risk factors for atherosclerosis and metabolic syndrome, and characterize nervous system involvement.

Our current research activities are focused on atherosclerosis, nervous system involvement, lupus nephritis, and damage accrual, and their economic impact using the inception cohort. New initiatives include development of a pregnancy cohort and working group on microparticles as well as revision of the SLICC/American College of Rheumatology (ACR) Damage Index (SDI).

SLE Criteria

SLE Criteria

SLICC classification criteria for Systemic Lupus Erythematosus SLICC PI: DR. MICHELLE PETRI

New Investigator: Dr. Ana-Maria Orbai

Funding Source: National Institutes of Health

Seventeen criteria were identified in a very time-consuming and laborious process which involved the consensus diagnosis of over 700 patient scenarios,

Seminal Contributions
SLICC Damage Index

SLICC Damage Index

SLICC Damage Index SLICC PI: DR. DAFNA GLADMAN

As chair of SLICC Dr. Gladman was a key facilitator in the development and validation of the SLICC/ACR Damage Index.

Seminal Contributions
Disease Flare Study

Disease Flare Study

Disease Flares SLICC PI: DR. DAVID ISENBERG

Funding Source: European League Against Rheumatism and American College of Rheumatology

Defining flare in patients with SLE is challenging.

Seminal Contributions